Showing posts with label Hormonal. Show all posts
Showing posts with label Hormonal. Show all posts

Migraine Treated

The first line of treatment is always to try and identify trigger factors, which means keeping a careful record of events, mainly of foods that have preceded an attack.
Particular foods are identified as migraine triggers in about 20 per cent of sufferers. The large female preponderance within migraine sufferers points to the importance of hormonal factors, such as the menstrual cycle, which are not modifiable.
Many women also find that the oral contraceptive pill worsens attacks, and if so it should be stopped. (Women who get migraines with aura, severe migraines regularly lasting over 72 hours despite treatment, or migraines that are treated with ergot medicines should not take the contraceptive pill.)
People suffering a migraine should try to rest in a dark, quiet room.
Treatment of migraine is most effective if given at the start of an attack.
Treatments for sufferers aged under 18 may differ from older patients, so it's important to discuss this with the pharmacist before buying any over the counter remedies.
They are all prescription medicines, with the exception of sumatriptan, which can now be bought from pharmacies as Imigran recovery. These drugs cause the blood vessels around the brain to contract, therefore counteracting the dilatation that seems to part of the initial migraine process.
They come in various forms, including nasal sprays, injections and tablets that dissolve on the tongue, which can be useful if nausea and vomiting are a problem during the migraine.
It's worth noting that using any painkillers for headaches or migraines too often or for too long can actually make the headaches worse. If you find you're getting frequent migraines and are often taking painkillers, it's important to consult your doctor for advice.
Often several kinds of medication need to be tried and perhaps combined before the most effective treatment for each individual patient can be found.
Alternative therapies, such as homoeopathy and acupuncture, are popular even if the evidence supporting their effectiveness is poor or absent.
The herbal remedy feverfew has shown some efficacy in preventing migraine and is available over the counter as Migraherb.
Lifestyle and dietary advice are always important.

Manage Your Life With Migraine Disease

The first migraine that I experienced was at the age of nineteen, approximately 2-3 weeks following the birth of my first child. It was quite horrible as I recall it... although worse migraine episodes occurred in the years to follow. My guess is that hormone changes were the onset factor in this episode. My first migraine was not looked upon with compassion by some of my family. My husband (we have since divorced) was less than sympathetic as he was unfamiliar to pain himself and did not understand how to relate to other people's pain. I also received the wrath of my then mother-in-law. She was angered that my husband was unable to escort his younger brother as planned that evening to a local baseball game because my husband was forced to stay home to care for our newborn while I was incapacitated. USA Today survey regarding Family Reaction to Migraine Sufferers indicated that our loved ones'reactions when migraines occur often range anywhere from understanding to resentment.

Hormonal Deficiencies

Most studies involving hormone deficiency and aging have focused on the relationship between individual hormones and specific age-associated disease. In a recently released study, scientists at the University of Pennsylvania School of Medicine investigated the possibility that frailty would mostly likely manifest in the presence of deficits in multiple hormones. They studied the relationships of serum levels of insulin-like growth factor-1 (IGF-1), DHEAS, and unbound testosterone with frailty status in aging women.
The study used 494 women aged 70 to 79 years who were enrolled in the Women's Health and Aging Studies I or II. Scientists calculated the odds of frailty for deficiency of each hormone, which they defined as the bottom quartile of hormone level. They found that for each hormone, those with a deficiency were more likely to be frail than those without a deficiency. Compared with women who showed no hormonal deficiencies, those with one deficiency were somewhat more likely to be frail. However, those women with two or three deficiencies had a very high likelihood of being frail. The odds ratio for frailty for these women was 2.79, meaning that women who were deficient in more than one hormone had almost a 3 times greater risk of being frail than women who were not hormonally deficient.
The scientists concluded that the absolute burden of hormonal deficiencies in the bodies of aging women was a stronger predictor of frailty status than the type of hormonal deficiency. They found the relationship to be exponential, and suggestive of generalized endocrine dysfunction in the frailty syndrome. This study may be found in the January 31 edition of Journals of Gerontology Series A Biological Sciences and Medical Sciences.

People diagnosed as frail lose the ability to care for themselves and live independently

Frailty is characterized by unexplained weight loss, exhaustion, weak grip, slow walking speed, and generalized low energy levels. Women who are frail are the most vulnerable, most at risk for disability or death, and are the highest users of medical care. In a nationwide study of 5,000 older adults, those who were frail were found to be six times more likely to die than those who were not over a three-year period, and more than three times more likely to die over a seven-year period. After seven years, 43 percent of those who were frail had died, compared to 23 percent of those who were classified as intermediate, and 12 percent of those who were robust.
A diagnosis of frailty is made based on symptoms such as shrinking (unintentional weight loss of at least 10 pounds or 5 percent of body weight compared to a year ago), weakness (grip strength in the lowest 20th percentile), poor endurance and energy (self-reported exhaustion), slowness (the most time it takes to walk 15 feet), and low physical activity level (the lowest 20 percent in physical activity compared to others).
Frail women have a very high incidence of osteoporosis. They are the most likely group to suffer falls that result in broken bones, and may even suffer broken bones without a fall. Frail women and men are the highest users of disease establishment services and are the most likely to be admitted to nursing homes.

Men with multiple hormonal deficiencies are more than twice as likely to die

Aging in men is also characterized by progressive decline in levels of hormones such as testosterone, IGF-1, and DHEAS. In a study at the National Institute on Aging, scientists investigated whether deficiencies in these hormones were associated with higher mortality. Testosterone, IGF-1, DHEAS, and demographic factors were evaluated in 410 men age 65 and older enrolled in the Aging in the Chianti Area Study.
The men were divided into four groups: no hormone in the lowest reference quartile, and 1, 2, and 3 hormones in the lowest quartiles. Compared with men having levels of all 3 hormones above the lowest quartiles, having 1, 2, and 3 deficient hormones was associated with hazard ratios for mortality of 1.47, 1.85, and 2.29. This means that men deficient in 3 hormones were more than two and one-quarter times more likely to die. The scientists concluded that age associated decline in hormone levels is a strong independent predictor of mortality in older men. Having multiple hormone deficiencies is a reliable biomarker of health status in older men. This study is from the November, 2007 Archives of Internal Medicine.

Hormonally deficient men with chronic heart failure have the poorest prognosis

In men with chronic heart failure, hormone depletion is common. A deficiency of each hormone is an independent marker of poor prognosis according to a study at the Military Hospital of Wroclaw, Poland. Serum levels of total testosterone, DHEAS, and IGF-1 were obtained from 208 men with chronic heart failure who were hospitalized or treated as outpatients, and from a reference population of 366 men free of chronic disease.
Deficiencies in DHEAS, total and unbound testosterone, and IGF-1, defined as serum levels at or below the 10th percentile of healthy peers, were seen across all age categories of men with chronic heart failure. DHEAS deficiency correlated positively with left ventricular disturbance. Testosterone measures and IGF-1 levels were prognostic biomarkers. Men with chronic heart failure and normal levels of all hormones had the best 3 year survival rate (83 percent) compared to those with 1 hormone deficiency (74 percent survival rate), 2 hormone deficiencies (55 percent survival rate), and 3 hormone deficiencies (27 percent) survival rate. This study is from the October 24, 2006 edition of Circulation.